DMILM laboratories are equipped with the following facilities:
- luminex based analyzer (LabScan 100)
- real time PCR
- ELISA platform
- new generation multiplate readers
- minion sequencing devise
- HPLC-MS
- FPLC
- Raman spectroscopy
- Absorbance reader
- Cell counter.
DMILM employs a team of laboratory specialists, biotechnologists as well as clinicians skilled in microbiology and immunology. Apart from research activity, DMILM also provides microbiological and immunological diagnostics for University clinics.
The expertise offered includes:
- Implementation of luminex-based multiplex technology.
- Bacterial genes expression.
- Bacterial and phage genome bioinformatics.
- Bacterial biofilm assays.
- Bacteriophage isolation, characterisation and preparation.
- Fungal taxonomy based on genomic analyses.
- In vitro drug-resistance induction and potentially novel antimicrobial agents testing.
- Complex data analysis.
- Translational approach towards data based on solid immunological background.
Additionally, due to diagnostic activity:
- PCR-SSP based human leucocytes antigens (HLA) assessment.
- Luminex-based anti HLA antibodies detection.
- RT-PCR-based BK virus and human cytomegalovirus replication detection.
- Autoantibodies detection based on indirect immunofluorescence and Western-blot.
The group is interested in cooperation in:
- Investigating the role of gut and urine microbiome in low grade inflammation.
- Bioinformatic analysis of uropathogenic Escherichia coli adhesines and their affinity towards host receptors.
- Targeting the role of gut microbiome in drugs metabolism.
- Investigating the role of the microbiome and the oxidative stress in shaping gut-brain axis.
- Investigating skin and bones microbiomes.
- Revising the opportunity of natural products application as potentially new antimicrobials, especially trans-anethole.
- Studies on Campylobacter and nosocomial K. pneumoniae strains-targeting virulence factors and drug-resistance mechanisms.
- Studies on the role of phages as potentially new antimicrobials and biofilm preventives.
- Application studies on novel diagnostic tool in systemic fungal infections.
Thematic area - Cluster in Horizon Europe: 1. Health